I don't know about you, but I want a whole lot more control over the sites I visit than I currently have. My facebook de-crap-ifier is the first step, but I want more. I want to be able to write plugins for specific sites that will be able to either hide or move content depending on what I care about. The primary example of this is the facebook news feed. I don't want to see sponsored crap, invites, notices about stupid shit, etc. If I could write a script that would be able to look at the tags returned by facebook, I could easily just catch those and throw them out before they get displayed.
This might be doable with a firefox plugin or something like that, so I'm going to look into it a little bit. The end goal would be to be able to strip as much crap from any pages I regularly visit so I only get what I need/want.
Update: the Greasemonkey plugin for Firefox is exactly what I needed. You should definitely check it out.